Production

Nichi-Iko rigorously manages its manufacturing and its quality control system in line with GMP (Good Manufacturing Practices) standards with a view to delivering high quality and cost-effective generic drugs. By doing so, we are constantly aiming to manufacture high quality drugs. In addition, we are working to enhance our expertise and a stable supply of high-quality and safe drugs through integration and reorganization of its production lines to match dosage forms in every plant.

Toyama Plant

Two plants, Toyama Plant 1 and Toyama Plant 2, are located in Namerikawa City, which are situated in the eastern part of Toyama Prefecture. Toyama Plant 1 comprises Honeycomb, a global development and quality control center, and the four production buildings of Pentagon, Pyramid, Obelisk, and Nexstage, and Toyama Plant 2 handles the packaging process for powders and granules.

The Obelisk Building of Toyama Plant 1 features a flexible design that can respond to changes in market trends by securing space for the future expansion. Together with the Pentagon and Pyramid Buildings, the Obelisk Building has an annual production capacity of 11.0 billion solid formulations at the time of full implementation, making it Japan’s largest oral formulation plant. In each building, each room has one machine and a perfectly clean environment is achieved by preventing the entry of foreign particles through cross contamination.

Toyama Plant 1

Toyama Plant 1

Lines Tablets & Capsules

Address 205-1 Shimo-Umezawa, Namerikawa-shi, Toyama Prefecture, Japan #936-0857

Site area 61,045m2

Toyama Plant 2

Toyama Plant 2

Lines Powder & Granules

Address 183-5 Yasuda, Namerikawa-shi, Toyama Prefecture, Japan #936-0825

Site area 6,600m2

Aichi Plant

The Aichi Plant is located in Kasugai City in Aichi Prefecture, which has an 80% share of seeding cacti in Japan. It is Nichi-Iko’s injection production plant with a site area of 20,000 m2.

Of the products handled by the Aichi Plant, 50%-plus consist of liquid-filled products, approximately 40% consist of antibiotics, and 10% comprise lyophilized (freeze-dried) products, with annual production totaling more than 54 million units.

To augment the annual production capacity of 90 million units of injections,we will additionally introduce the latest freeze dryers in an effort to manufacture freeze-dried products in-house as we make a shift away from contract manufacturing of such products.

  • Aichi Plant
  • Aichi Plant

Lines Liquid, injections and lyophilizations (freeze-dried)

Address 1212 Aza-teramae, Gejo-cho, Kasugai-shi, Aichi Prefecture, Japan #486-0923

Site area 20,000m2

Saitama Plant

The Saitama Plant is located in Saitama City in Saitama Prefecture. Although it is not a large plant, with a site area of 7,000 m2, it handles the manufacturing of value-added products such as Nichi-Iko’s oral jellies, eye drops, and plastic bottle for single administration.

The oral jelly can be completely pressed out effortlessly by means of Nichi-Iko’s unique airpush packaging. Furthermore, the eye drops and plastic bottle for single administration to be manufactured using a simultaneous molding and filling system utilizes an innovative system that tightly seals the container after simultaneously molding the container and filling it with liquid.

  • Saitama Plant

Lines Added value preparations (oral jelly, ophthalmic)

Address 51 Sanjyou-machi, Nishi-ku, Saitama-shi, Saitama Prefecture, Japan #331-0056

Site area 7,233m2

Yamagata Plant

The Yamagata Plant is located in Tendo City in Yamagata Prefecture, which is a famous for shogi pieces production. With a site area of approximately 7,000 m2, the Yamagata Plant handles the manufacturing of the Company’s external drugs, primarily heparinoid, a mainstay product of Nichi-Iko.

Regarding the manufacture of heparinoid, a fully automated, integrated line has been introduced, making it possible to conduct manufacturing while being completely cut off from outside air due to full in-line manufacturing.

  • Yamagata Plant Provided by SS Inc. Tohoku Office

Lines Externals (lotions, cream)

Address 2-1-52 Ishidorii, Tendo-shi, Yamagata Prefecture, Japan #994-0057

Site area 7,235m2

Shizuoka Plant

The Shizuoka Plant is located in Fuji City in Shizuoka Prefecture, offering a view of Mt. Fuji, which was registered as a world heritage site in 2013. With a site area of 110,000 m2, the Shizuoka Plant is larger than two Tokyo Dome stadiums in total area and produces general products and injections.
Formulation Building No. 1 has the technology to efficiently carry out manufacturing in large batches and a production line for general products with an annual production capacity of 4.0 billon tablets.
Formulation Building No. 2, which has an annual production capacity of 10 million injections, is completely isolated from Formulation Building No. 1. It is a production line for antibiotic liquid injections.

Shizuoka Plant

Lines General preparations (including tablets, capsules, granules), antibiotic liquid injections

Address 88 Nakagawara, Fuji-shi, Shizuoka Prefecture, Japan #417-8588

Site area 110,000m2

Hokkaido Plant

The Hokkaido Plant is located in Kitahiroshima City in Hokkaido, which is known as “the vast land of the north.” It delivers trust and assurance to our customers by providing reliable disinfectant/antiseptic.

The Hokkaido Plant manufactures various disinfectants/antiseptics such as alcohols, iodines, biguanides, and surfactants, which are widely used for disinfecting the human body and medical equipment/environments mainly at medical institutions.

Hokkaido Plant

Lines Antiseptics, JP listed drugs

Address 27 Kitanosato, Kitahiroshima-shi, Hokkaido, Japan #061-1111

Site area 23,117m2